Tremfya 100mg Injection contains the active ingredient Guselkumab, a human monoclonal antibody used to treat chronic inflammatory disorders, including moderate to severe plaque psoriasis and active psoriatic arthritis. It belongs to a class of medicines known as interleukin-23 (IL-23) inhibitors, which help reduce inflammation caused by an overactive immune response. Tremfya 100mg Injection is prescribed for adults who are eligible for systemic therapy or phototherapy. It works by selectively targeting IL-23, a protein involved in the abnormal immune activity seen in psoriasis and psoriatic arthritis. This helps improve skin symptoms and reduce joint inflammation. Common side effects may include upper respiratory tract infections, headaches, fatigue, joint pain, diarrhea, and injection site reactions. If you experience signs of a serious allergic reaction, infection, or breathing difficulty, contact your healthcare provider immediately.
• Moderate to severe plaque psoriasis in adults who are candidates for systemic treatment or phototherapy
• Active psoriatic arthritis in adults, either alone or in combination with other disease-modifying antirheumatic drugs (DMARDs)
Tremfya subcutaneous injection binds specifically to the p19 subunit of interleukin-23 (IL-23), preventing it from activating inflammatory pathways. By blocking this protein, the Tremfya 100 mg ml injector reduces skin plaques and joint pain, offering long-term control of chronic inflammatory diseases. It helps lower immune system overactivity without broadly suppressing immunity.
Common Side Effects:
• Serious allergic reactions (rash, swelling, difficulty breathing)
• Increased risk of infections such as tuberculosis (TB)
• Liver enzyme abnormalities
• Reactivation of latent infections (like hepatitis B)
Administered as a subcutaneous injection under the skin.
• Pregnancy: Use with caution. Limited data is available on Tremfya 100mg Injection use during pregnancy. Consult your doctor if you are pregnant or planning to conceive.
• Breast Feeding: The safety of Tremfya 100mg Injection during breastfeeding is not fully established. Use only when absolutely necessary, and only under medical supervision.
• Lungs: Inform your doctor if you have a history of tuberculosis (TB) or chronic lung disease before starting treatment.
• Liver: There is no strong evidence suggesting liver toxicity, but caution is advised in patients with liver impairment.
• Alcohol: There are no known interactions with alcohol, but limit alcohol intake if your psoriasis symptoms are aggravated by it.
• Driving: Tremfya 100mg Injection is not known to affect your ability to drive. However, if you feel dizzy or unwell after the injection, avoid driving or using machinery.